DNA Protection by an Aronia Juice-Based Food Supplement

Background: This study investigated the effects of an aronia juice-based food supplement on background and total DNA strand breaks in whole blood, H2O2-induced isolated peripheral blood lymphocytes. Methods: Ninety-one healthy volunteers were randomly selected to consume either (2 × 25 mL drinking ampules, n = 45) or no (n 46) daily for eight weeks. Results: Background decreased significantly after four weeks consumption, compared baseline (p < 0.05), but overall effect was low, neither group showed a decrease breaks. Conversely, consumption clearly reduced ex vivo 0.001), with statistically significant reductions weeks, control 0.05). Conclusions: Thus, although consuming antioxidant supplements might produce only marginal immediate benefits under conditions, potential preventive warrant further investigation.